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The srd a isoforms showed
2023-11-13
The srd5a isoforms showed unique expression profiles in early FHM development (Fig. 2). Similar to amphibian embryos, there was a high abundance of both srd5a1 and srd5a3 at 1dpf in FHMs, suggesting that mRNA for these enzymes may be maternally deposited and that these enzymes may play a key role in
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br The role of cytochrome b with cytochrome P hydroxylase
2023-11-13
The role of cytochrome b5 with cytochrome P450 17α-hydroxylase/17,20-lyase Conclusion Acknowledgments LLM and RJR wish to thank the Australian Research Council and the National Health and Medical Research Council of Australia for funding. The problem One area of modern medicine that con
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If the lack of specificity and the high pleiotropy
2023-11-13
If the lack of specificity and the high pleiotropy may represent a problem in view of the potential chemotherapeutic features of autophagy-inducing agents, it Retigabine dihydrochloride receptor may switch into an advantage in the case of chemopreventive strategies. In fact, as non-pharmacologic in
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br Acknowledgements M M M
2023-11-13
Acknowledgements M.M.M. is the William Dow Lovett Professor of Neurology and is supported by grants from the Michael J. Fox Foundation for Parkinson's Research, the American Parkinson Disease Association, the New Jersey Health Foundation/Nicholson Foundation, and by the National Institutes of He
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br Experimental section br Acknowledgments br Introduction A
2023-11-13
Experimental section Acknowledgments Introduction Adipose is a major endocrine organ which releases a range of bioactive agents [1]. Selected adipose depots have been established as sites of sex steroid metabolism [1]. Subcutaneous and visceral adipose express high levels of aromatase, cap
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br Materials and methods br Results
2023-11-13
Materials and methods Results RT-PCR showed that both arginase 1 and 2 were expressed in the OB of Korean roe deer (Fig. 1). Immunoblotting detected arginase 1 in the OB of roe deer (Fig. 2A, left lane) at a molecular weight of approximately 37kDa, which is the size of the enzyme in the rat O
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br Acknowledgments This study is a part of a MSc
2023-11-13
Acknowledgments This study is a part of a MSc thesis and supported by Scientific Research Projects Coordination Unit of Akdeniz University (grant number: 2011.02.0122.007). Introduction Apelin receptor (putative receptor protein related to the angiotensin receptor AT1, APJ) belongs to the G-p
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br Antioxidant polymers conjugates Natural antioxidants
2023-11-13
Antioxidant-polymers conjugates Natural antioxidants are usually used as a substitute for synthetics but some degradation phenomena could influence their applications. For example, ascorbic ap-1 transcription factor as a natural antioxidant undergoes yellowish coloration as a result of oxidation
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In a human intervention study blood
2023-11-13
In a human intervention study, blood GSH levels were evaluated over 6 wk in 18 male participants subjected to strenuous aerobic training and a dietary supplement of 1 g of WPI/kg of body mass per day. Blood GSH levels were significantly lower in those subjects who performed exercise that those who d
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br Author contributions br Financial disclosures br
2023-11-13
Author contributions Financial disclosures Acknowledgements We thank Ms. Eva So for the editorial assistance. This work was supported by grants from the National Natural Science Foundation of China (No. 81622015, 81571042 and 81501143) and the National Basic Research Program of China (No. 2
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br Disclosures br Author contributions br Grants This
2023-11-13
Disclosures Author contributions Grants This work was supported by National Institutes of Health/National Heart, Lung, and Blood Institute MERIT Award R37 HL040696 to J.A.F. Acknowledgments Introduction The AGC kinases, named after the protein A, G and C kinases, are an evolutionaril
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To guide our attempts at achieving AKT
2023-11-13
To guide our attempts at achieving AKT potency and selectivity against p70S6K and other kinases from (p70 S6K IC: 0.004 μM) and , we took advantage of exploiting the subtle sequence differences in the active sites of the AGC family kinases, we utilized the information around crystal structure of AK
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Teriflunomide It is also possible that adrenoceptor activati
2023-11-13
It is also possible that α2-adrenoceptor activation may inhibit glutamate accumulation by upregulating the glutamate-buffering activity of Müller Teriflunomide through EAAT1 or adjusting EAAT2 in bipolar cells, as well as the NMDA receptor. Therefore, we investigated whether topical administration
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A number of studies suggest that adiponectin promotes osteob
2023-11-10
A number of studies suggest that adiponectin promotes osteoblast differentiation and bone formation by directly targeting GSK-3β and β-Catenin signaling [64], [65], favoring bone marrow mesenchymal stem cell (BMSC) differentiation toward the osteoblastic lineage [66], [67], decreasing sympathetic to
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The physiological effect of adenosine is now considered
2023-11-10
The physiological effect of adenosine is now considered a new direction in halting the progression of organ damage in cardiovascular disease [24], [25], [26]. Adenosine has diverse functions, depending on its interaction with different receptor subtypes: A1, A2A, A2B, and A3[24], [25], [26]. Stimula
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