• We have previously shown that sustained

  2019-07-02

  

  We have previously shown that sustained 8-pCPT treatment favored Ca2+-dependent arrhythmogenic activity in rat ventricular cardiomyocytes [8]. Fig. 2 shows line-scan Ca2+ images of myocyte incubated without (Fig. 2A left) and with 8-pCPT (Fig. 2A right) subjected to a train of electrical stimulation

• Quantum dots QDs which exhibit excellent fluorescence quantu

  2019-07-02

  

  Quantum dots (QDs), which exhibit excellent fluorescence quantum yields (QYs), high extinction coefficients and size-tunable narrow emission have highly attracted great interest in various applications such as in solar cells, sensors, and bioimaging [16], [17], [18], [19], [20]. However, QDs suffere

• In astrocytes mitogen activated protein kinases MAPKs are ac

  2019-07-01

  

  In astrocytes, mitogen-activated protein kinases (MAPKs) are activated after OGD-induced ischemic injury (Yung and Tolkovsky, 2003, Niu et al., 2009) and they regulate induction of AQP expression (Arima et al., 2003, McCoy and Sontheimer, 2010). It is well known that MAPKs, including extracellular s

• In summary synthetic routes with moderate to high yields hav

  2019-07-01

  

  In summary, synthetic routes with moderate to high yields have been developed to produce difluoro-dioxolo-benzoimidazol-benzamides including reference standards and , and -desmethylated precursors and , and carbon-11-labeled difluoro-dioxolo-benzoimidazol-benzamides target tracers [C] and [C]. The

• After a decade of political and economic

  2019-07-01

  

  After a decade of political and economic crisis between 1999 and 2010, health education in Zimbabwe was in a desperate state and required a major overhaul. UZCHS reported a 60% decrease in medical student enrolment, a 61% faculty vacancy rate, a 50% increase in failure rate, and the specialist train

• Reframing non communicable diseases NCDs to

  2019-07-01

  

  Reframing non-communicable diseases (NCDs) to “spur a sense of urgency” and “focus attention on effective system-wide interventions” makes sense. With almost three-quarters of NCD deaths now occurring in low-income and middle-income countries (LMICs), the increasing burden of NCDs already has sever

• The incidence of AF in Japan was

  2019-07-01

  

  The incidence of AF in Japan was also reported from an early cohort of the Hisayama Study [32] in the period between 1961 and 1984. Similar to the reports from Western countries, the incidence of AF increased with age in both men and women (Fig. 7) [32]. In a recent report of an observational cohort

• br Contributors br Funding br Conflict of interest br Patien

  2019-07-01

  

  Contributors Funding Conflict of interest Patient consent Ethics approval Acknowledgment Introduction Perforation of a cardiac chamber has been reported as a relatively rare complication of pacemaker implantation; in particular, attachment of the active-fixation atrial lead to t

• El recorrido inicia con una revisi n

  2019-07-01

  

  El recorrido inicia con una revisión de las colaboraciones de Paz en la revista entre la que destaca la del número 197, de marzo de 1951. El famoso de David Rousset en torno lrrk2 los campos de concentración en la . Lo que marcaría la ruptura de Paz con la izquierda stalinista latinoamericana. Kin

• Ya en el siglo xx

  2019-07-01

  

  Ya en el siglo xx, la Historia verdadera (y las crónicas de Indias en general) ha sido recuperada como origen de la literatura latinoamericana contemporánea, en especial por escritores vinculados casr la literatura del boom: Alejo Carpentier, Gabriel García Márquez, Carlos Fuentes. De hecho, Fuentes

• No conviene ignorar la enorme

  2019-07-01

  

  No conviene ignorar la enorme influencia cultural de Estados Unidos en la formación intelectual de Vasconcelos, so pena de caer en contradicciones. Ulises criollo se asienta en una tradición muy estadounidense, la de una fascinación por las cuestiones de la individualidad, la identidad y la autobiog

• La expansi n exportadora de

  2019-07-01

  

  La expansión exportadora de Argentina hacia Colombia, Perú y Venezuela respondió ONX-0914 molecular distintas razones, pero los mercados obviamente tuvieron mucho que ver. No fue casual que Colombia, por ejemplo, concentrara más de 65% de sus importaciones de Argentina en bienes primarios, pues la a

• Ad Mapu lleg a convertirse en

  2019-07-01

  

  Ad Mapu llegó Tubastatin A convertirse en un gran referente que contribuyó al fortalecimiento de la conciencia de la situación mapuche, así lo explica Víctor Toledo al mencionar que es en este momento cuando aparece bosquejada la autodeterminación como propuesta del pueblo mapuche, y recuerda las pa

• br Commentary Careful analysis of the electrocardiograph Fig

  2019-06-29

  

  Commentary Careful analysis of the electrocardiograph (Fig. 1) reveals narrow and similar QRS complexes in all the beats, showing that they are all intrinsic QRS complexes. Some intrinsic P waves are also visible at the ST-T segment (after R3, R7, R11, and R15); these are the beats without any sp

• This Ca overload activates the

  2019-06-29

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

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