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br Discussion Intriguingly in a case report about
2019-05-04
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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br CaMKII and heart failure
2019-04-30
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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This time last year to coincide with March launched
2019-04-30
This time last year, to coincide with (March 9), launched a to highlight the rising burden of kidney disease and to encourage research partnerships to address gaps in knowledge and care, including the affordability of such care. Nephrology research and collaboration has come a relatively long way si
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Some patients developed osmotic demyelination disease
2019-04-30
Some patients developed osmotic demyelination disease (ODS) after rapid correction of hyponatremia. Predisposing factors to development of ODS were syndrome of inappropriate antidiuretic hormone, alcoholism, liver cirrhosis, liver transplantation, renal failure, burns, malnutrition, or neoplasm. Oth
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MCL has a poor long term response
2019-04-30
MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens
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br Conflicts of interest br Acknowledgment This work
2019-04-30
Conflicts of interest Acknowledgment This work was supported, in part, by a grant from the Experimental Research Center ELPEN (Y97/2-12-2013). The funding source had no involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and in
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Long marginalised as a disorder confined
2019-04-30
Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th
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La imagen de Calanchina publicada en
2019-04-30
La imagen de Calanchina publicada en la Revista Alero fue el esquema que se utilizó para éste y otros murales, completando la transferencia con la interpretación de los jóvenes desde su postura ideológica. Si bien es un homenaje BLZ945 Robin, contiene referencia a la lucha popular, como fue señalado
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Leptin synthesized in adipocytes is a regulator of
2019-04-30
Leptin, synthesized in adipocytes, is a regulator of fat metabolism and reproduction [7]. The levels of leptin correlate with body fat mass and show a wide variation in individuals. In the bone marrow microenvironment, the leptin secreting adipocytes occupy a significant part [8]. Leptin stimulates
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Several studies suggested that for young males the risk
2019-04-29
Several studies suggested that for young males, the risk of TRUSP biopsy may outweigh its benefit. Yoo et al. reported that in Korean subjects younger than 40 years of age who received TRUSP biopsy, febrile urinary tract infections occurred in 3 patients (6%), 2 (4%) of whom needed hospitalization.
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br TAMs role in bone
2019-04-29
TAMs\' role in bone metastasis and primary bone cancer: evidence from preclinical and clinical studies The majority of preclinical and clinical studies assess TAMs in primary tumours and metastasis-associated macrophages (MAMs) in visceral metastases (e.g. lung, liver, kidney, spleen, brain). Som
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Case reports br Discussion RV perforation is a rare
2019-04-29
Case reports Discussion RV perforation is a rare but serious complication of PPM and ICD implantation. It is diagnosed when at least the tip of a passive fixation lead or the screw of an active fixation lead passes through the myocardium and extends into the pericardial cavity [1]. This complica
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Esta idea del l mite como un espacio o
2019-04-29
Esta idea del límite como un espacio o un estado que Z-IETD-FMK nuevas imágenes de la vida y de las experiencias corresponde con el epígrafe al presente artículo, donde Octavio Paz identifica el dualismo como una condición de “la sabiduría” (1996a: 17). Es útil tener en mente que los límites no son
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Desde el punto de vista de Antileo el camino hacia
2019-04-29
Desde el punto de vista de Antileo el camino hacia la liberación no debiera establecer una división descalificadora de las luchas y acciones de los mapuche que han salido de las comunidades, pues el radicalismo que cuestiona su legitimidad por estar fuera de ellas no permite verlos como agentes de r
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The G S mutation is extremely rare In the
2019-04-28
The G571S mutation is extremely rare. In the study by Ma et al. [6] approximately 20,000 blood samples from patients with suspected myeloproliferative neoplasms were analyzed for JAK2 mutations. The G571S mutation was found in only 3 samples, compared to the V617F mutation which was positive in 4280
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