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The promoter regions of all MdDGKs examined
2019-08-17
The promoter regions of all MdDGKs examined here included many hormone-responsive and stress-responsive elements, such as ABRE, MBS, TC-rich repeats, HSE, and LTR. Despite assumptions about how those promoters might control expression in response to environment stimuli, we found several exceptions.
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ApicomplexansApicomplexans are unicellular and spore forming
2019-08-17
ApicomplexansApicomplexans are unicellular and spore-forming obligate intracellular parasites that occupy diverse host niches (Mogi and Kita 2010). They have remodeled mitochondrial carbon and energy metabolism through reductive evolution. The development of novel drugs is now a very serious challen
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Currently approved anti obesity drugs for long
2019-08-17
Currently approved anti-obesity drugs for long term use such as orlistat, lorcaserin and liraglutide are efficient in reduction of weight gain but are limited in usage due to their adverse effect profile and higher cost (Krentz et al., 2016; Mopuri and Islam, 2017). In BVT 2733 to this, plant deriv
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br Conclusion Our objective is to promote cell activity
2019-08-16
Conclusion Our objective is to promote cell activity on biomaterials, especially for use in regenerative medicine, by grafting THPs containing collagen-binding sites onto inert substrates. We have previously reported a methodology to derivatize EDC/NHS crosslinked films with photoreactive THPs.
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Inopportunely normal aging brings about decreases in
2019-08-16
Inopportunely, normal aging brings about decreases in frontal D1 receptor densities and a gradual decline in postsynaptic markers of dopamine in striatal, neocortical, and limbic areas of the adenosine receptor agonist (Bäckman et al., 2006, de Keyser et al., 1990, Karrer et al., 2017, Suhara et al.
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The BDNF Val Met polymorphism is also associated with decrea
2019-08-16
The BDNF Val66Met polymorphism is also associated with decreased dendritic arborization and impaired long-term potentiation [25]. This is particularly important for the hippocampus, and healthy individuals with a BDNF Val66Met allele have decreased hippocampal volumes [30]. Hippocampal atrophy is co
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br Acknowledgments This study was
2019-08-16
Acknowledgments This study was supported by grants from the Spanish Ministry of Economy and CompetitivenessPI10/00387, PI12/01087, PI12/01703, IPT-2011-0817-010000, and RIC Red de Investigación Cardiovascular (RIC)RD12/0042/0055. RIC is an initiative of Instituto de Salud Carlos III (ISCIII), Spa
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The human MARCH family comprises
2019-08-16
The human MARCH family comprises eleven members (termed MARCH-1 to 11), of which nine are transmembrane proteins. In this review, we focus on the role of the membrane-spanning MARCH proteins and how their transmembrane regions can mediate interactions with their target proteins. Therefore, the cytos
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Also our data from this study indicate that
2019-08-16
Also, our data from this study indicate that gestational GC exposure altered hematological and hemorheological parameters, however reports exist that altered blood rheological markers are associated with atherosclerosis and CVD (Tzoulaki et al., 2007). Also, the platelet to lymphocyte ratio (PLR) ha
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It is conceivable however that the distortion induced
2019-08-16
It is conceivable, however, that the distortion induced by adozelesin in dsDNA may decrease the processivity of the translocating RecBCD enzyme so that it dissociates more frequently from adducted DNA relative to unmodified DNA. Premature termination from the DNA would also produce partially unwound
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br Introduction Lung cancer is the leading cause of
2019-08-16
Introduction Lung cancer is the leading cause of cancer-related death worldwide, accounting for more than 1.5 million deaths in 2012. Non–small-cell lung cancers represent approximately 85% of lung neoplasms; among these, squamous cell carcinomas (SCC) account for approximately 30% of cases. The
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br Acknowledgments br Introduction Cysteinyl leukotrienes
2019-08-16
Acknowledgments Introduction Cysteinyl leukotrienes (CysLTs), LTC4, LTD4 and LTE4, are 5-lipoxygenase pathway metabolites of arachidonic DL-Menthol and deeply involved in bronchial asthma via activation of CysLT1 receptors [1], [2]. Specific CysLT1 receptor antagonists, including pranlukast [
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Citrus plants are of great interest because
2019-08-16
Citrus plants are of great interest because they contain large amounts of flavonoids, and citrus fruits and their juices are consumed in large quantities around the world [18]. The flavonoid contents and profiles of citrus juices vary greatly with the type of fruit. It has been determined that citru
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In recent years neuroimaging studies
2019-08-15
In recent years, neuroimaging studies have increasingly demonstrated acute effects of THC on Navitoclax function, the vast majority of them involving a cognitive challenge (Bossong et al., 2014b). For example, without affecting performance accuracy, THC caused reductions in activity during encoding
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Magnetic interactions between metal ions are usually describ
2019-08-15
Magnetic interactions between metal ions are usually described by superexchange via intermediate ligands. Although the general principles of the superexchange mechanism are essentially the same for d and f ions, calculations of exchange parameters for lanthanides are more difficult than for transiti
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